Ambroxol HCl (NA-872 hydrochloride) 是前药溴己新的活性代谢物，具有强效祛痰作用。
| Cas No. | 23828-92-4 |
| 别名 | 盐酸氨溴索,NA-872 hydrochloride |
| 化学名 | 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydrochloride |
| Canonical SMILES | C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl |
| 分子式 | C13H18Br2N2O.HCl |
| 分子量 | 414.56 |
| 溶解度 | ≥ 164.6mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3. |
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