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Bomedemstat ditosylate(IMG 7289)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bomedemstat ditosylate(IMG 7289)图片
CAS NO:1990504-72-7
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
Bomedemstat ditosylate (IMG7289) is a novel, potent and orally bioavailable small molecule discovered and developed by Imago BioSciences that inhibits lysine-specific demethylase 1 (LSD1 or KDM1A), an enzyme shown to be vital in cancer stem/progenitor cells, particularly neoplastic bone marrow cells. In non-clinical studies, bomedemstat demonstrated robust in vivo anti-tumor efficacy across a range of myeloid malignancies as a single agent and in combination with other chemotherapeutic agents. Bomedemstat is an investigational agent currently being evaluated in ongoing clinical trials (ClinicalTrials.gov Identifier: NCT03136185, NCT04262141 and NCT04081220). Bomedemstat has FDA Orphan Drug and Fast Track Designation for the treatment of myelofibrosis and essential thrombocythemia, Orphan Drug Designation for treatment of acute myeloid leukemia and PRIME designation by the European Medicines Agency for the treatment of MF.
理化性质和储存条件

Molecular Formula: C42H50FN7O8S2;

Exact Mass: 863.3146;

Molecular Weight: 864.0214

Synonyms: IMG7289 ditosylate; IMG-7289; IMG 7289; Bomedemstat ditosylate