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Laurolitsine hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Laurolitsine hydrochloride图片
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议

产品介绍
Laurolitsinehydrochloride是从台湾雅楠中分离到的生物碱类化合物，具有轻微的抗炎功效。
别名(+)-Norboldine hydrochloride
Canonical SMILESOC1=C(OC)C2=C3C(CCN[C@@]3([H])CC4=CC(O)=C(OC)C=C24)=C1.[H]Cl
分子式C18H20ClNO4
分子量349.81
溶解度DMSO: 83 mg/mL (237.27 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Laurolitsine hydrochloride is an alkaloid isolated from Phoebe formosana, and shows weak anti-inflammatory activity.

Laurolitsine shows weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells[1]. Boldine, laurolitsine and litebamine (300 μM) remarkedly inhibit the aggregation of rabbit platelets induced by arachidonic acid (100 μM) and collagen (10 μM/mL), and slightly inhibit that induced by ADP (20 μM)[2].

[1]. Zhang SY, et al. [Alkaloids from roots and stems of Litsea cubeba]. Zhongguo Zhong Yao Za Zhi. 2014 Oct;39(20):3964-8. [2]. Teng CM, et al. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol. 1997 Jul;49(7):706-11.