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(R)-α-Lipoic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(R)-α-Lipoic Acid图片
CAS NO:1200-22-2
包装与价格：
包装价格(元)
1g电议
5g电议
10g电议
25g电议

产品介绍
(R)-α-Lipoic acid is the naturally occurring enantiomer of lipoic acid, a cyclic disulfide antioxidant.
Cas No.1200-22-2
别名硫辛酸; (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid
Canonical SMILESO=C(CCCC[C@H]1SSCC1)O
分子式C8H14O2S2
分子量206.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:8): 0.25 mg/ml
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.

Lipoic acid ((R)-(+)-α-Lipoic acid) is the form biosynthesized in humans which is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α-Lipoic acid) constitute the racemic mixture Lipoic acid. Only the Lipoic acid ((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) has been suggested to be nutritionally and therapeutically preferred form as antioxidant[1].

References:
[1]. Nasole E, et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. J Enzyme Inhib Med Chem. 2014 Apr;29(2):297-302.