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11-trans Leukotriene C4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
11-trans Leukotriene C4图片
CAS NO:74841-69-3
包装与价格：
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
Cas No.74841-69-3
Canonical SMILESCCCCC/C=C\C/C=C/C=C/C=C/[C@@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)[C@@H](O)CCCC(O)=O
分子式C30H47N3O9S
分子量625.8
溶解度DMF: >50 mg/ml (per Ramki Iyer),DMSO: >50 mg/ml (per Ramki Iyer),Ethanol: >50 mg/ml (per Ramki Iyer),PBS pH 7.2: >100 µ g/ml (per Ramki Iyer)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum as a cysteinyl leukotriene receptor preparation, the pKis for LTC4 and 11-trans LTC4 were determined to be 6.42 and 6.58, respectively.