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5(S),12(S)-DiHETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5(S),12(S)-DiHETE图片
CAS NO:79056-01-2
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.
Cas No.79056-01-2
Canonical SMILESCCCCC/C=C\C[C@H](O)/C=C/C=C\C=C\[C@@H](O)CCCC(O)=O
分子式C20H32O4
分子量336.5
溶解度DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.