| Cas No. | 1143573-33-4 |
| 化学名 | 2-[[1-[3-[4-([1,1'-biphenyl]-4-ylcarbonyl)-2-propylphenoxy]propyl]-1,2,3,4-tetrahydro-5-quinolinyl]oxy]-2-methyl-propanoic acid |
| Canonical SMILES | CC(C)(C(O)=O)OC1=CC=CC2=C1CCCN2CCCOC3=CC=C(C(C4=CC=C(C5=CC=CC=C5)C=C4)=O)C=C3CCC |
| 分子式 | C38H41NO5 |
| 分子量 | 591.7 |
| 溶解度 | DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. The prototypical compound for this class is the TZD rosiglitazone (BRL 49653), which is currently marketed for the treatment of diabetes. CAY10599 is a PPARγ agonist that is 4-fold more potent than rosiglitazone at the PPARγ receptor demonstrating an EC50 value of 0.05 uM. This compound shows high selectivity for PPARγ over PPARα (EC50 = 3.99 uM) or PPARδ (EC50 >10 uM). |
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