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6-NBDG
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
6-NBDG图片
CAS NO:108708-22-1
包装与价格：
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
6-NBDG 是一种荧光葡萄糖类似物，可用于荧光成像和监测葡萄糖转运和摄取。
Cas No.108708-22-1
化学名6-deoxy-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
Canonical SMILESO[C@H]1[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]1CNC2=CC=C([N+]([O-])=O)C3=NON=C23
分子式C12H14N4O8
分子量342.3
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: slightly soluble,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

6-NBDG is a non-hydrolyzable fluorescent glucose analog that is used to monitor glucose uptake and transport in living cells. 6-NBDG has been validated as a probe for the glucose transporter GLUT1 in cells. The fluorophore NBD displays excitation/emission maxima of 465/535 nm.

References:

1. Hansen, T.V.A., Hansen, M., Nejsum, P., et al. Glucose absorption by the bacillary band of Trichuris muris PLoS Negl. Trop. Dis. 10(9), e0004971 (2016).
2. Wang, M.S., Luo, Z., and Nitin, N. Rapid assessment of drug response in cancer cells using microwell array and molecular imaging Anal. Bioanal. Chem. 406(17), 4195-4206 (2014).
3. Zaman, R.T., Kosuge, H., Pratx, G., et al. Fiber-optic system for dual-modality imaging of glucose probes 18F-FDG and 6-NBDG in atherosclerotic plaques PLoS One 9(9), e108108 (2014).
4. Barros, L.F., Bittner, C.X., Loaiza, A., et al. Kinetic validation of 6-NBDG as a probe for the glucose transporter GLUT1 in astrocytes J. Neurochem. 109(Suppl 1), 94-100 (2009).