Cas No. | 5094-14-4 |
别名 | 13,14-二氢-15-酮-前列腺素E1 |
化学名 | 9,15-dioxo-11α-hydroxy-prostan-1-oic acid |
Canonical SMILES | O[C@H]1[C@H](CCC(CCCCC)=O)[C@@H](CCCCCCC(OC)=O)C(C1)=O |
分子式 | C20H34O5 |
分子量 | 354.5 |
溶解度 | DMF: >100 mg/ml (from PGE1),DMSO: >50 mg/ml (from PGE1),Ethanol: >50 mg/ml (from PGE1),PBS pH 7.2: >1.6 mg/ml (from PGE1) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 uM, respectively, compared to PGE1 which has an IC50 of 40 nM. |