| CAS NO: | 664338-39-0 |
| 包装 | 价格(元) |
| 250mg | 电议 |
| 500mg | 电议 |
| Cas No. | 664338-39-0 |
| 别名 | 青蒿氧烷; OZ 277; RBx 11160 |
| Canonical SMILES | O=C(NCC(N)(C)C)C[C@H](CC1)CC[C@]21OO[C@]3(O2)[C@H]4C[C@@H]5C[C@H](C4)C[C@H]3C5 |
| 分子式 | C22H36N2O4 |
| 分子量 | 392.53 |
| 溶解度 | DMSO : 100 mg/mL (254.76 mM) |
| 储存条件 | Store at -20°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1]. [1]. Vennerstrom JL, et al. Identification of an antimalarial synthetic trioxolane drug development candidate. Nature. 2004 Aug 19;430(7002):900-4. |
m.cnreagent.com