AC-VEID-CHO (TFA) is a peptide-derivedcaspaseinhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 withIC₅₀values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. AC-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease^[1].

AC-VEID-CHO (TFA) has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀values of 16.2 nM, 13.6 nM and 162.1 nM, respectively^[1].
Ac-VEID-CHO is predominantly excluded from accessing the intracellular environment (0.16% cellular accumulation) and lacks any activity with an IC₅₀value of ＞100 μM in the cellular assay^[1].
AC-VEID-CHO (TFA) (also inactive in lamin degradation assay) is clearly able to inhibit VEIDase activity with an IC₅₀value of 0.49 μM when the membrane barrier is removed^[1].

614.57

Solid

C₂₄H₃₇F₃N₄O₁₁

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 1 mg/mL(1.63 mM;Need ultrasonic and warming)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。