Pemetrexed (LY-231514; LY231514; HSDB7316; HSDB-7316; trade name Alimta), a synthetic pyrimidine-based antifolate, is antimetabolite anticancer drug that inhibits TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed exhibits high autitumor activity in a broad range of tumors such as NSCLC/non-small cell lung carcinoma, malignant mesothelioma, and carcinomas of the breast, colorectum, uterine cervix, head and neck, and bladder.

纯度：≥98%

CAS：137281-23-3