Tauroursodeoxycholate-d4 (Tauroursodeoxycholic acid-d4) sodium is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression ofapoptosismolecules, such ascaspase-3andcaspase-12. Tauroursodeoxycholate also inhibitsERK.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

525.71

C₂₆H₄₀D₄NNaO₆S

2410279-95-5

牛磺熊去氧胆酸钠 d4 (钠盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.