Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversiblcaspase-3inhibitor with anIC₅₀of 23 nM. Ivachtin has modest selectivity for the remaining caspases^[1].

Ivachtin (Caspase-3 Inhibitor VII; compound 7a; 10, 100 μM) has protective effect in a model of staurosporininduced apoptosis in human Jurkat T cells^[1].

447.46

Solid

C₂₀H₂₁N₃O₇S

745046-84-8

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)