Paraherquamide E 是一种在夏氏青霉中发现的真菌代谢物。
Cas No. | 125600-53-5 |
别名 | 对郝喹酰胺E |
Canonical SMILES | CC(C=CO1)(C)OC2=C1C(NC([C@]34C[C@](CN(CC[C@@H]5C)[C@]5(C6=O)C7)(N6C)[C@]7([H])C3(C)C)=O)=C4C=C2 |
分子式 | C28H35N3O4 |
分子量 | 477.6 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Paraherquamide E is a fungal metabolite originally isolated from P. charlesii with anthelmintic and insecticidal activities. It is lethal to C. elegans (LD50 = 6 μg/ml). Paraherquamide E is also lethal to O. fasciatus (LD50 = 0.089 μg/nymph). Oral administration of paraherquamide E (0.5-4 mg/kg) reduces T. colubriformis fecal egg count in gerbils. |