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Marcfortine A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Marcfortine A图片
CAS NO:75731-43-0
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Cas No.75731-43-0
别名麦可弗汀A
Canonical SMILESCC1(C)OC2=CC=C3C(NC([C@]34C(C)(C)C(C[C@@](CCCC5)(C(N6C)=O)N5C7)[C@@]76C4)=O)=C2OC=C1
分子式C28H35N3O4
分子量477.6
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.