CAS NO: | 1310877-95-2 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Methylstat is a potenthistone demethylasesinhibitor. Methylstat shows anti-proliferative activity with low cytotoxicity. Methylstat inducesapoptosisand cell cycle arrest at G0/G1 phase. Methylstat increases the expression ofp53and p21 protein levels. Methylstat inhibits angiogenesis induced by various cytokines. Methylstat can be used as a chemical probe for addressing its role in angiogenesis[1][2]. | ||||||||||||||||||||||||||||||||||||||||
体外研究 (In Vitro) | Methylstat (0-5 μM; 48, 72 h) shows anti-proliferative activity with no cytotoxicity on HUVECs at 1-2 μM[1]. Cell Cytotoxicity Assay[1]
Cell Viability Assay[1]
Cell Cycle Analysis[1]
Western Blot Analysis[1]
Apoptosis Analysis[2]
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分子量 | 505.56 | ||||||||||||||||||||||||||||||||||||||||
性状 | Solid | ||||||||||||||||||||||||||||||||||||||||
Formula | C28H31N3O6 | ||||||||||||||||||||||||||||||||||||||||
CAS 号 | 1310877-95-2 | ||||||||||||||||||||||||||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||||||||||||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||||||||||||||||||||||||||
溶解性数据 | In Vitro: DMSO : 100 mg/mL(197.80 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |