Epiblastin A 是一种 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂,对 CK1α, CK1δ, 和CK1 e 的IC50分别为 8.9, 0.5,和 4.7 μM。Epiblastin A 通过抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。
生物活性 | Epiblastin A is an ATP competitivecasein kinase1(CK1) inhibitor withIC50s of 8.9, 0.5, and 4.7 μM for CK1α, CK1δ, andCK1e, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition ofCK1[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |