CAS NO: | 480-23-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
生物活性 | Orobol is one of the major soyisoflavonesand has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibitsCK1ε, VEGFR2, MAP4K5,MNK1, MUSK,TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibitsPI3Kisoforms (IC50=3.46-5.27 μM forPI3Kα/β/γ/K/δ)[1][2]. | ||||||||
体外研究 (In Vitro) | Orobol binds to CK1ε in an ATP-competitive manner and exerts anti-obesity effects by targeting casein kinase 1 epsilon[2]. | ||||||||
体内研究 (In Vivo) | Orobol attenuates high fat diet-induced weight gain and lipid accumulation without affecting food intake in C57BL/6J mice[2].
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分子量 | 286.24 | ||||||||
Formula | C15H10O6 | ||||||||
CAS 号 | 480-23-9 | ||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |