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Aniracetam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aniracetam图片
CAS NO:72432-10-1
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
100mg电议
250mg电议

产品介绍
阿尼西坦 (Ro 13-5057) 是一种口服活性神经保护剂,具有促智作用。
Cas No.72432-10-1
别名茴拉西坦; Ro 13-5057
化学名1-(4-methoxybenzoyl)pyrrolidin-2-one
Canonical SMILESCOC1=CC=C(C=C1)C(=O)N2CCCC2=O
分子式C12H13NO3
分子量219.24
溶解度≥ 10.96mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Aniracetam is a nootropic drug in senile dementia [1].

Aniracetam (Ro 13-5057) has a piracetam-like chemical structure, 1-p-anisoyl-2-pyrrolidinone. It is selected from a series of related compounds because of its effect in impaired cognitive functions in rodents. In rats, the administration of aniracetam (30mg/kg orally) markedly prevents the CO2 induced impairment of acquisition. It also significantly increases the percentage of rats showing retention of the learned task in both the scopolamine induced transient retrograde amnesia model (50mg/kg orally) and the electroconvulsive shock induced memory disruption model (50mg/kg orally). Besides that, aniracetam can prevent the disruptive effect caused by chloramphenicol or cycloheximide (30mg/kg orally) [1, 2].

References:
[1] MIZUKI Y, YAMADA M, KATO I, et al. Effects of aniracetam, a nootropic drug, in senile dementia. A preliminary report.: A Preliminary Report. The Kurume medical journal, 1984, 31(2): 135-143.
[2] Cumin R, Bandle E F, Gamzu E, et al. Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. Psychopharmacology, 1982, 78(2): 104-111.