CDK1/Cyc B-IN-1

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CDK1/Cyc B-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2459916-56-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

CDK1/Cyc B-IN-1 (Compound 5) 是一种选择性的CDK1/Cyc B复合体抑制剂，IC₅₀为 97 nM。CDK1/Cyc B-IN-1 诱导细胞凋亡 (apoptosis) 和 G2/M 细胞期阻滞。CDK1/Cyc B-IN-1 对癌细胞具有广谱的细胞毒性。

生物活性

CDK1/Cyc B-IN-1 (Compound 5) is a selectiveCDK1/Cyc Bcomplex inhibitor with anIC₅₀of 97 nM. CDK1/Cyc B-IN-1 triggersapoptosisand G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action againstcancercell lines^[1].

IC₅₀& Target

CDK1-Cyclin B

97 nM (IC₅₀)

体外研究
(In Vitro)

CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC₅₀values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively^[1].

分子量

353.85

Formula

C₁₄H₁₂ClN₃O₂S₂

CAS 号

2459916-56-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.