CAS NO: | 2650640-17-6 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | CDK9-IN-14 is a potent and selectiveCDK9inhibitor withIC50of 6.92 nM. CDK9-IN-14 has a relatively strong inhibitory effect on MV4;11 cells andin vivotumor models, and has a good selectivity and a low toxicity and few side effects[1]. | ||||||||
IC50& Target[1] |
| ||||||||
体外研究 (In Vitro) | CDK9-IN-14 (0-1000 nM) has strong inhibitory effect in MV4;11 cells with IC50= 34 nM[1]. | ||||||||
体内研究 (In Vivo) | CDK9-IN-14 (5 mg/kg; p.o., qd, for 9 days) exhibits significant anti-tumor effect with tumor growth inhibition (TGI) value of 58%[1].
| ||||||||
分子量 | 419.42 | ||||||||
Formula | C21H23F2N3O4 | ||||||||
CAS 号 | 2650640-17-6 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |