CAS NO: | 2413603-15-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | HDAC6-IN-5 (compound 11b) is a potent and BBB-penetratedHDAC6inhibitor, with anIC50of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity againstAβ1-42self-aggregation andAChE, withIC50values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity[1]. | ||||||||||
IC50& Target |
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体外研究 (In Vitro) | HDAC6-IN-5 (compound 11b) induces histone H3 and α-tubulin acetylation in a dose-dependent manner, withEC50values of 0.58 and 8 μM, respectively[1] | ||||||||||
分子量 | 408.25 | ||||||||||
Formula | C20H14BrN3O2 | ||||||||||
CAS 号 | 2413603-15-1 | ||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |