PI3K/HDAC-IN-1 是一种有效的(PI3K/HDAC)双重抑制剂，高效抑制 PI3Kδ 和 HDAC1 的IC50值分别为 8.1 nM 和 1.4 nM。
| 生物活性 | PI3K/HDAC-IN-1 is a potent dual inhibitor ofPI3K/HDAC, potently inhibitsPI3KδandHDAC1withIC50s of 8.1 nM and 1.4 nM, respectively[1]. |
| IC50& Target | PI3Kα 42 nM (IC50) | PI3Kβ 101 nM (IC50) | PI3Kγ 67 nM (IC50) | PI3Kδ 8.1 nM (IC50) | HDAC1 1.4 nM (IC50) | HDAC2 3.0 nM (IC50) | HDAC6 6.6 nM (IC50) | HDAC8 18 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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