HDAC10-IN-2 (化合物 10c) 是一种有效的和高选择性的HDAC10抑制剂，其IC50为 20 nM。HDAC10-IN-2 可调节侵袭性 FLT3-ITD 阳性急性髓系白血病细胞的自噬。
| 生物活性 | HDAC10-IN-2 (compound 10c) is a potent and highly selectiveHDAC10inhibitor, with anIC50of 20 nM. HDAC10-IN-2 modulatesautophagyin aggressive FLT3-ITD positive acute myeloid leukemia cells[1]. |
| IC50& Target | HDAC10 20 ± 2 nM (IC50) | hHDAC8 470 ± 70 nM (IC50) | hHDAC6 3700 ± 450 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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