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Msr-Ratio
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Msr-Ratio图片
CAS NO:2290635-22-0
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Msr-Ratio(Msr-green)是一种比率型甲硫氨酸亚砜还原酶(methioninesulfoxidereductase)的荧光探针(Λex=375nm,Λem=550nm)。Msr-Ratio可用于监测体外和活细胞中的甲硫氨酸亚砜还原酶活性。
Cas No.2290635-22-0
别名Msr-green
Canonical SMILESCS(C1=CC=C(/C=C/C(OC2=C3C=CC=C2)=CC3=O)C=C1)=O
分子式C18H14O3S
分子量310.37
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (Λex=375 nm, Λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells[1].

Msr-Ratio is converted to its corresponding sulfide form by methionine sulfoxide reductase. Msr-Ratio displays favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large Stokes shift (120 nm), and green emission (550 nm)[1].There is a very weak background signal in live HL60 cells after the addition of Msr-Ratio. As the Msr-Ratio (10 μM) incubation time increased in cells from 0 to 8 h, the fluorescence signal constantly strengthened[1].

[1]. Liangwei Zhang, et al. A ratiometric fluorescent probe of methionine sulfoxide reductase with an improved response rate and emission wavelength. Chem Commun (Camb). 2019 Jan 29;55(10):1502-1505.