您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > Decylubiquinone
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Decylubiquinone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Decylubiquinone图片
CAS NO:55486-00-5
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
癸基泛醌是泛醌（辅酶 Q10）的类似物。
Cas No.55486-00-5
别名癸基泛醌
化学名2-decyl-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
Canonical SMILESCOC(C(C(CCCCCCCCCC)=C1C)=O)=C(OC)C1=O
分子式C19H30O4
分子量322.4
溶解度10mg/mL in DMSO, or in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Decylubiquinone is an analog of ubiquinone . It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. [1] Decylubiquinone inhibited opening of the mitochondrial permeability transition pore in response to calcium overload in rat liver mitochondria in different cell lines at concentrations between 50-100 &#181M.[2]

Reference:
[1]. Armstrong, J.S., Whiteman, M., Rose, P., et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: Role of mitochondrial complex III. J. Biol. Chem. 278(49), 49079-49084 (2003).
[2]. Devun, F., Walter, L., Belliere, J., et al. Ubiquinone analogs: A mitochondrial permeability transition pore-dependent pathway to selective cell death. PLoS One 5(7), (2010).