PAIR2 是一种有效和选择性的IRE1α RNase的部分拮抗剂。PAIR2 可以完全占据细胞中 IRE1α 的 ATP 结合位点，并阻断强效 KIRA 抑制 XBP1 剪接的能力。
| 生物活性 | PAIR2 is a potent and selective partial antagonist ofIRE1α RNase. PAIR2 can completely occupy IRE1α’s ATP-binding site in cells and block the ability of a potent KIRA to inhibit XBP1 splicing[1]. |
| Clinical Trial | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
m.cnreagent.com
