PROTAC PARP1 degrader是基于MDM2E3配体的PARP1降解剂。它可显著诱导PARP1剪切和程序性死亡。在10 μM,24 h时,PROTAC PARP1 degrader抑制MDA-MB-231的IC50值为6.12 μM。
生物活性 | PROTACPARP1 degrader is aPARP1degrader based onMDM2E3 ligand. It induces significantPARP1cleavage and programmed cell death.PROTACPARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with anIC50of 6.12 μM. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |