Midostaurin-D5 (PKC412-D5) 是 Midostaurin 的氘代化合物。Midostaurin 是一种多靶点蛋白激酶抑制剂,抑制PKCα/β/γ,Syk,Flk-1,Akt,PKA,c-Kit,c-Fgr,c-Src,FLT3,PDFRβ和VEGFR1/2的活性,IC50值为 22-500 nM。
生物活性 | Midostaurin-D5 (PKC412-D5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibitsPKCα/β/γ,Syk,Flk-1,Akt,PKA,c-Kit,c-Fgr,c-Src,FLT3,PDFRβandVEGFR1/2withIC50s ranging from 22-500 nM[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |