CAS NO: | 2636771-29-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PKC-IN-4 (compound 7l) is a potent and orally activeaPKCinhibitor with anIC50of 0.52 μM. PKC-IN-4 inhibits TNF-α inducedNF-κBactivity in vitro. PKC-IN-4 blocks VEGF- and TNFα-induced permeability across the retinal vasculature[1]. | ||||||||
IC50& Target[1] |
| ||||||||
体外研究 (In Vitro) | PKC-IN-4 (compound 7l) shows VEGF - induced endothelial permeability with anEC50of 0.071 μM[1]. | ||||||||
体内研究 (In Vivo) | PKC-IN-4 (10 mg/kg for i.v.; 20 mg/kg for p.o.) shows orally active with oral bioavailability of 81.7%[1].
| ||||||||
分子量 | 379.52 | ||||||||
Formula | C21H25N5S | ||||||||
CAS 号 | 2636771-29-2 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |