CAS NO: | 149055-79-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | WAY-100135 dihydrochloride is a selective antagonist at presynaptic and postsynaptic5-HT1Areceptor, with anIC50of 34 nM at the rat hippocampal 5-HT1Areceptor. WAY-100135 dihydrochloride has potential antipsychotic properties[1][2]. | |
IC50& Target[1] |
| |
体外研究 (In Vitro) | WAY100135 (0.1-1 μM) antagonises electrically evoked contractions of 5-carboxamidoiodotryptamine in the guinea-pig ileum, with a pA2of 7.2[1]. | |
体内研究 (In Vivo) | WAY100135 (2.5 mg/kg) induces a maximum 30% inhibition of raphe neuronal firing and (0.5 mg/kg i.v.) antagonises the inhibition of firing induced by 8-OH-DPAT in anaesthetised rats[1]. | |
分子量 | 468.46 | |
Formula | C24H35Cl2N3O2 | |
CAS 号 | 149055-79-8 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |