CAS NO: | 54810-23-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Loxapine hydrochloride is an orally activedopamineinhibitor,5-HT receptorantagonist and also a dibenzoxazepine anti-psychotic agent[1][4]. | ||||||||
IC50& Target |
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体外研究 (In Vitro) | In the presence of Loxapine, [3H]ketanserin binds to 5-HT2receptor in Frontal cortex of brain in human and bovine with Kivalue of 6.2 nM and 6.6 nM, respectively. Loxapine has the rank order of potency for the various receptors appears to be as follows: 5-HT2≥D4>>>D1>D2in comparing competition experiments involving the human membranes[1]. | ||||||||
体内研究 (In Vivo) | Loxapine (5 mg/kg; i.p.; daily for 4 or 10 weeks) decreases serotonin (S2) but does not elevate dopamine (D2) receptor numbers in the rat brain[3].
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Clinical Trial | |||||||||
分子量 | 364.27 | ||||||||
Formula | C18H19Cl2N3O | ||||||||
CAS 号 | 54810-23-0 | ||||||||
中文名称 | 盐酸洛沙平 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |