CAS NO: | 1245626-00-9 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | AM6538 is a long-acting, high affinity and pseudo-irreversiblecannabinoid (CB)antagonist. AM6538 is a structural analog of rimonabant. AM6538 can be effectively used to evaluate the apparent efficacy of cannabinoid full and partial agonists. AM6538 may be useful in future studies that require temporary reductions incannabinoid receptoravailability[1]. | ||||||||||||||||
IC50& Target | cannabinoid[1] | ||||||||||||||||
体外研究 (In Vitro) | AM6538 is a cannabinoid antagonist that binds CB1 receptors expressed in HEK-293 cells in a wash-resistant manner[1]. | ||||||||||||||||
体内研究 (In Vivo) | AM6538 (1~10 mg/kg) antagonizes the antinociceptive effects of cannabinoid agonists in mice[1]. | ||||||||||||||||
分子量 | 542.41 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C26H25Cl2N5O4 | ||||||||||||||||
CAS 号 | 1245626-00-9 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(92.18 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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