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Eicosapentaenoyl Ethanolamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eicosapentaenoyl Ethanolamide图片
CAS NO:109001-03-8
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Eicosapentaenoyl ethanolamide 是 omega-3 脂肪酸,一种 N-酰基乙醇胺 (NAE)。Eicosapentaenoyl ethanolamide 是大麻素CB1/CB2受体激动剂。Eicosapentaenoyl ethanolamide 是一种代谢信号。Eicosapentaenoyl ethanolamide 抑制饮食限制 (DR) 诱导的野生型动物寿命延长,并抑制 TOR 通路突变体的寿命延长。
生物活性

Eicosapentaenoyl ethanolamide, an omega-3 fatty acid, is one of N-acylethanolamines (NAEs). Eicosapentaenoyl ethanolamide iscannabinoid CB1/CB2 receptoragonist. Eicosapentaenoyl ethanolamide acts as a metabolic signal. Eicosapentaenoyl ethanolamide inhibits dietary restriction (DR)-induced lifespan extension in wild typeanimalsand suppresses lifespan extension in a TOR pathway mutant[1][2].

IC50& Target[1]

CB1

 

CB2

 

体外研究
(In Vitro)

Eicosapentaenoyl ethanolamide (EPEA) induces cell death in both LNCaP and PC3 cells (IC50=16.19 μM). EPEA (24 hours) did not result in any significant changes in the G1, S or G2phases of the cell cycle[1].

分子量

345.52

Formula

C22H35NO2

CAS 号

109001-03-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.