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DSP-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DSP-4图片
CAS NO:40616-75-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
DSP-4 是一种高度选择性的肾上腺素能神经毒素。
Cas No.40616-75-9
别名Neurotoxin DSP 4 hydrochloride
化学名N-(2-bromobenzyl)-2-chloro-N-ethylethanamine hydrochloride
Canonical SMILESBrC1=CC=CC=C1CN(CC)CCCl.Cl
分子式C11H15BrClN.HCl
分子量313.06
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
储存条件Desiccate at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC)[1][2].

References:
[1]. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
[2]. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.