CAS NO: | 73226-73-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 73226-73-0 |
别名 | FR900098味精盐 |
Canonical SMILES | CC(N(O)CCCP([O-])(O)=O)=O.[Na+] |
分子式 | C5H11NO5P•Na |
分子量 | 219.1 |
溶解度 | DMF: Inso,DMSO: Inso,Ethanol: Inso,PBS (pH 7.2): 5mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner. FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice. |