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Ebselen Oxide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ebselen Oxide图片
CAS NO:104473-83-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Ebselen oxide 是 Ebselen 的硒酮类似物,共价修饰二鸟苷酸环化酶 (DGC) 以抑制 c-di-GMP-受体相互作用并降低 DGC 活性。
Cas No.104473-83-8
别名NSC 639772
化学名1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
Canonical SMILESO=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
分子式C13H9NO2Se
分子量290.2
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): .15 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.[1]

Reference:
[1]. Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochimica et Biophysica Acta 1303, 111-118 (1996).