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DPTA NONOate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DPTA NONOate图片
CAS NO:146724-95-0
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Cas No.146724-95-0
别名3,3'-(羟基亚硝基肼)二-1-丙胺,Dipropylenetriamine NONOate
化学名(Z)-1-[N-(3-aminopropyl)-N-(3-ammoniopropyl)amino]diazen-1-ium-1,2-diolate
Canonical SMILES[NH3+]CCCN(N(N=O)[O-])CCCN
分子式C6H17N5O2
分子量191.2
溶解度Highly soluble in water
储存条件Store at -80℃ sealed under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DPTA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37℃ and 22-25℃, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound. [1][2]

Reference:
[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods in Enzymology 268, 281-293 (1996).