CB1R Allosteric modulator 3

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CAS NO:

2633686-36-7

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

CB1R Allosteric modulator 3 是 CB1R 正变构调制器。CB1R Allosteric modulator 3 对 cAMP 和 β-Arrestin 具有较强的抑制作用，其EC₅₀值分别为 0.018 μM 和 1.241 μM。

生物活性

CB1R Allosteric modulator 3 is aCB1R positive allosteric modulator. CB1R Allosteric modulator 3 has potent inhibition of cAMP and β-Arrestin withEC₅₀values of 0.018 μM and 1.241 μM, respectively^[1].

IC₅₀& Target

CB1

体外研究
(In Vitro)

CB1R Allosteric modulator 3 (compound 44) (0.10 nM-10 μM, 30 min) has potent inhibition of cAMP and β-Arrestin with EC₅₀values of 0.018 μM and 1.241 μM, respectively^[1].
CB1R Allosteric modulator 3 can enhance CB1R ago-PAM activity because of small lipophilic functional groups on the ortho-position of the GAT211 site-III phenyl ring^[1].

分子量

376.84

Formula

C₂₂H₁₇ClN₂O₂

CAS 号

2633686-36-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.