COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor ofcylooxygenaseand5-lipoxygenase (5-LO), used for the research of inflammatory and allergic disease states.

COX/5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4, and E4 and cyclooxygenase products such as prostaglandins and thromboxane and are useful in the treatment of inflammatory and allergic disease states^[1]. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase, with IC₅₀of 0.2 μM in human whole blood^[2].

318.37

C₁₆H₁₅FN₂O₂S

154355-75-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.