CAS NO: | 83881-51-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamineH1-receptorantagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3]. | ||||||||
体外研究 (In Vitro) | Cetirizine (>5 μM) at higher concentrations can reduce the release of GM-CSF and IL-8 from A549 cells stimulated with IL-1β. Cetirizine exerts anti-inflammatory effects beyond histamine H1-receptor antagonist[2]. Cell Viability Assay[2]
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体内研究 (In Vivo) | Cetirizine (20 mg/kg, mice, orally) exerts its anti-inflammatory effects by inhibiting MIF as well as IL-8 production in mice immunized and challenged with ragweed pollen[3].
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Clinical Trial | |||||||||
分子量 | 388.89 | ||||||||
Formula | C21H25ClN2O3 | ||||||||
CAS 号 | 83881-51-0 | ||||||||
中文名称 | 西替利嗪;西替利嗪 | ||||||||
结构分类 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. | ||||||||
溶解性数据 | In Vivo:
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