CAS NO: | 70059-30-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Cimetidine (SKF-92334) hydrochloride is an orally active and inversehistamine H2 receptorantagonist with aKiof 0.6 μM. Cimetidine hydrochloride is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine hydrochloride has anti-cancer and anti-inflammatory activity[1][2][5]. | ||
IC50& Target[1] |
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体外研究 (In Vitro) | Cimetidine (SKF-92334) hydrochloride, a partial agonist for H2R, has a pharmacological profile different from ranitidine and famotidine, possibly contributing to its antitumor activity on gastrointestinal cancers [1]. Cimetidine hydrochloride has no effect on the uptake and cytotoxicity of cisplatin in ovarian cancer cells with high OCT2 mRNA levels (IGROV-1 cells)[3]. | ||
体内研究 (In Vivo) | Cimetidine (SKF-92334) hydrochloride reduces CD11b(+)Gr-1(+) myeloid derived-suppressive cell (MDSC) accumulation in spleen, blood and tumor tissue of tumor-bearing mice[4]. | ||
Clinical Trial | |||
分子量 | 288.80 | ||
Formula | C10H17ClN6S | ||
CAS 号 | 70059-30-2 | ||
中文名称 | 盐酸西咪替丁;盐酸甲氰咪胍;盐酸甲氰咪胺 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |