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Bimekizumab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1418205-77-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
Anti-Human IL17A/IL-17F Recombinant Antibody
产品介绍
Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) 是一种人源化单克隆抗体,可选择性中和IL-17AIL-17F。这两种细胞因子都能够促进成骨的人骨膜衍生细胞 (hPDC) 分化。因此,Bimekizumab 的应用,可以阻断炎症驱动的成骨分化。
生物活性

Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralisesIL-17AandIL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation[1].

IC50& Target[1]

IL-17A

 

IL-17F

 

体外研究
(In Vitro)

Bimekizumab (10 μg/mL; 1 h) results dual neutralisation of IL-17A and IL-17F, leads to osteocommitment of hPDCs by AS serum is suppressed[1].

性状

Liquid

CAS 号

1418205-77-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.