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Sulfacetamide Sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sulfacetamide Sodium图片
CAS NO:127-56-0
规格:≥98%
包装与价格:
包装价格(元)
1g电议
2g电议
5g电议
10g电议
100g电议
200g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)236.22
FormulaC8H10N2O3S.Na
CAS No.127-56-0
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 19 mg/mL (80.4 mM)
Water: 51 mg/mL (215.9 mM)
Ethanol: <1 mg/mL
SMILESO=S(NC(C)=O)(C1=CC=C(N)C=C1)=O.[Na+]
SynonymsNSC63871; NSC-63871; NSC 63871; Sulfacetamide; Region; Sebizon
实验参考方法
In Vitro

In vitro activity: Sulfacetamide is a sulfonamide antibiotic. Sulfacetamide is able to inhibit the growth of all isolated strains. Depending on the type of bacteria concentrations of 0.006 up to 6.4% sodium sulfacetamide proved to be effective. Simultaneously, all patients were treated with sulfacetamide containing ointment and/or eye drops 4 times daily for maximum of 14 days. With swabs taken at intervals of 7 and 14 days no bacterial growth was detected. Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. Sulfacetamide has been investigated for use in the treatment of pityriasis versicolor and rosacea. It may also have anti-inflammatory properties when used to treat blepharitis or conjunctivitis. It is believed to work by limiting the presence of folic acid which bacteria need to survive. It has been suggested that sulfacetamide may also serve as a treatment for mild forms of hidradenitis suppurativa. Sulfacetamide has antibacterial activity and is used to control acne. Some research indicates that sulfacetamide derivatives may act as antifungals by an CYP51A1-independent mechanism

In Vivo
Animal model
Formulation & Dosage
References

Klin Monbl Augenheilkd. 1992 Mar;200(3):182-6; Met Based Drugs. 2000;7(1):49-54.