包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | MS9449 is a potentPROTACEGFRdegrader withKds of 17 nM and 10 nM forEGFRWT andEGFRL858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer[1]. | ||
IC50& Target[1] |
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分子量 | 1151.82 | ||
Formula | C60H76ClFN10O8S | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |