Nitidine chloride 是一种来自花椒 (Roxb) DC 的潜在抗疟疾先导化合物,通过多种途径发挥有效的抗癌活性,包括诱导细胞凋亡、抑制 STAT3 信号级联、DNA 拓扑异构酶 1 和 2A、ERK 和 c-Src/FAK 相关信号通路。
Cas No. | 13063-04-2 |
别名 | 氯化两面针碱 |
化学名 | 2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;chloride |
Canonical SMILES | C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC.[Cl-] |
分子式 | C21H18ClNO4 |
分子量 | 382.82 |
溶解度 | ≥ 1.9 mg/mL in DMSO with ultrasonic and warming,<1.93 mg/mL in EtOH,<1.91 mg/mL in Water |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Extracted from Radix zanthoxyli;Store the product in sealed, cool and dry condition |