Taraxerone

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Taraxerone

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

514-07-8

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议
10mg	电议
50mg	电议

产品名称

蒲公英赛酮

产品介绍

Taraxerone 是从垂盆草中分离出来的。Taraxerone 增强乙醇脱氢酶 (ADH) 和乙醛脱氢酶 (ALDH) 活性，EC₅₀值分别为 512.42 μM 和 500.16 μM。

生物活性

Taraxerone is isolated fromSedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities withEC₅₀values of 512.42 and 500.16 μM, respectively^[1].

IC₅₀& Target

EC50: 512.42 μM (ADH); 500.16 μM (ALDH)^[1]

体内研究
(In Vivo)

Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure^[1].
Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration^[1].

分子量

424.70

性状

Solid

Formula

C₃₀H₄₈O

CAS 号

514-07-8

中文名称

蒲公英赛酮

结构分类

Terpenoids
Triterpenes

来源

Plants
Compositae
Taraxacum mongolicumHand.-Mazz.

Plants
Crassulaceae
Sedum sarmentosumBunge

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:

THF : 10 mg/mL(23.55 mM;Need ultrasonic)

DMSO :< 1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble or slightly soluble)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.3546 mL	11.7730 mL	23.5460 mL
5 mM	0.4709 mL	2.3546 mL	4.7092 mL
10 mM	0.2355 mL	1.1773 mL	2.3546 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。