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ALDH1A3-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ALDH1A3-IN-1图片
CAS NO:1695970-90-1
包装与价格:
包装价格(元)
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产品介绍
ALDH1A3-IN-1 (Compound 14) 是一个有效的ALDH1A3抑制剂,其IC50值为 0.63 μM,Ki值为 0.46 μM。ALDH1A3-IN-1 能被用于研究前列腺癌 (prostate cancer)。
生物活性

ALDH1A3-IN-1 (Compound 14) is a potentALDH1A3inhibitor, with anIC50of 0.63 μM and aKiof 0.46 μM. ALDH1A3-IN-1 can be studied inprostatecancer[1].

IC50& Target

ALDH1A3

0.63 μM (IC50)

ALDH1A1

7.08 μM (IC50)

ALDH3A1

8.00 μM (IC50)

ALDH1A3

0.46 μM (Ki)

ALDH1A3

26.92 μM (Km)

体外研究
(In Vitro)

ALDH1A3-IN-1 (Compound 14) (0-200 μM, 96 h) shows antiproliferative activity in prostate cancer cell lines[1].
ALDH1A3-IN-1 (0-200 μM, 72 h) reduces cell viability of primary prostate cells in a dose-dependent manner[1].

Cell Proliferation Assay[1]

Cell Line:PC3, LNCaP, and DU145 cells
Concentration:12.5-200 μM
Incubation Time:96 h
Result:Showed antiproliferative activity with IC50values of 47 ± 6, 25 ± 1, and 61 ± 5 μM against PC3, LNCaP, and DU145 cells.

Cell Viability Assay[1]

Cell Line:Primary cells cultured at early passage from human prostate tissue biopsies
Concentration:50 and 200 μM
Incubation Time:72 h
Result:Resulted a dose-dependent reduction in percentage cell viability of primary prostate epithelial cultures.
分子量

284.19

性状

Liquid

Formula

C13H18BrNO

CAS 号

1695970-90-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)