CAS NO: | 59736-84-4 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
Cas No. | 59736-84-4 |
Canonical SMILES | O=S(NC1=CC=C(C=C1)C(O)=O)(C2=CC(NC(C3=CC=C(OC)C=C3)=O)=CC=C2/C=C/C4=CC=C(NC(C5=CC=C(OC)C=C5)=O)C=C4S(NC6=CC=C(C=C6)C(O)=O)(=O)=O)=O |
分子式 | C44H36N4O12S2 |
分子量 | 876.91 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU. MtbHU-IN-1 (SD4) is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with Kds of 98 nM, 760 nM, 980 nM, 340 nM and 730 nM for WT and mutant MtbHUs, respectively[1]. [1]. Bhowmick T, et al. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors. Nat Commun. 2014 Jun 11;5:4124. |